Chronischer Pruritus
نویسندگان
چکیده
Zusammenfassung Chronischer Pruritus ist ein häufiges Symptom mit einer Prävalenz von rund 15 %. Neben klassischen Hauterkrankungen wie der atopischen Dermatitis oder Psoriasis leiden auch zahlreiche Patienten internistischen, neurologischen und psychiatrischen Krankheitsbildern an Pruritus. Die häufigsten internistischen Ursachen des chronischen sind chronische Niereninsuffizienz, Leber- Gallengangerkrankungen, lymphoproliferative Neoplasien sowie Medikamentennebenwirkungen. Seltener endokrinen metabolischen Störungen, Malassimilationssyndromen, Infektionskrankheiten soliden Tumoren betroffen. Basistherapie besteht aus rehydrierenden rückfettenden Topika. Bei chronischer Niereninsuffizienz die Wirksamkeit Kalziumkanalblocker Gabapentin Pregabalin gut belegt. Agonisten κ‑Opioidrezeptors stellen neuartige Therapieansätze dar. hepatobiliären Erkrankungen werden Gallensäurebinder, Rifampicin, Fibrate, μ‑Opioidrezeptor-Antagonisten Antidepressiva eingesetzt. Zukünftig ileale Gallensalz-Wiederaufnahme(IBAT)-Hemmer Anwendung finden. lymphoproliferativen häufig JAK-STAT-Inhibitoren effektiv.
منابع مشابه
Pruritus vulvae.
Anogenital irritation is a fairly common complaint by women in a general practitioner's surgery. No age group is exempt, if nappy rash is included, but strictly speaking pruritus is itching or irritation rather than soreness. In this region pruritus is a particularly distressing complaint because to attempt to relieve it by scratching is socially unacceptable. For this reason, parents may consu...
متن کاملChronic pruritus.
Chronic pruritus is one of the most frequent complaints of the skin associated with a high disease burden and markedly impaired quality of life. Chronic pruritus (>6 weeks of duration) may occur in a broad variety of diseases including dermatological, systemic, neurological, psychosomatic/psychiatric and gynaecological ones and in every age group (children, adults, pregnant women, elderly patie...
متن کاملPruritus Ani
Pruritus ani is an unpleasant cutaneous sensation that induces the desire to scratch the skin around the anal orifice. It may start insidiously and appears in 1% to 5% of the population. It is classified as primary (idiopathic) pruritus ani when no cause can be found. However, as 25% to 75% of cases have co-existing pathology, a detailed history and examination are necessary. The goal of treatm...
متن کاملPruritus vulvae
Pruritus vulvae can have infectious as well as noninfectious causes. In sexually active women, infectiousborne pruritus is mainly caused by vulvovaginal candidiasis. However, also changes in the bacterial flora can cause itching and burning. In persistent and regressing cases, we also have to consider non-infectious dermatoses. Here, the most common disease is lichen sclerosus, not only present...
متن کاملBewertung von Therapieoptionen bei Kindern und Jugendlichen mit chronischer Immunthrombozytopenie
Approximately 70% of children have the acute form of immune thrombocytopenia (ITP), which is defined by recovery within six months of presentation with or without treatment. Chronic ITP is to be reserved for patients with platelets < 100 000/μl for more than twelve months and exclusion of other diagnosis like systemic lupus erythematosus or bone marrow failures. In children, the chance of spont...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Schweizer Gastroenterologie
سال: 2022
ISSN: ['2662-7159', '2662-7140']
DOI: https://doi.org/10.1007/s43472-022-00063-5